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KMID : 1151820150090060357
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Journal of the Korean Society of Radiology
2015 Volume.9 No. 6 p.357 ~ p.362
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The Study on Usefulness of the Standardized Information of Nuclear Medicine Scan in Function Evaluation of the Salivary Glands
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Pyo Sung-Jai
Han Jae-Bok
Choi Nam-Gil
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Abstract
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This study was to evaluate the usefulness through the comparison of patients group and healthy control group by acquiring a variety of functional parameters index from time-activity curves of salivary gland scan using 99mTc-pertechnetate. From December 2014 to February 2015, had the targets of 30 patients with dry mouth and 10 people in healthy control group underwent the salivary gland scan. After intravenous injection of 370 MBq of 99mTc-pertechnetate, Vitamin C powder stimulation was administerd orally at 20 min and then 10 minutes were taken scan. The method of quantitative analysis was as follows, the time-activity curve was drawn after the parotid gland and submandible gland were prescribed as a region of interest, a variety of function parameters index was obtained in each position of the curve, and the patients group and the control group were compared. As for the methods applied in comparison and measurement, uptake ratio (UR), time at maximum counts (Tmax), time at minimum counts (Tmin), maximum accumulation (MA), accumulation velocity, maximum secretion (MS), maximum stimulation secretion (MSS), and secretion velocity (SV) were used. In the comparison of functional parameters index of patient group and normal group, the healthy normal group showed significant difference compared to the patient group in all indices except for the minimum radioactivity time (Tmin), and also in terms of variation over time the normal group showed significant difference compared to the patient group (p<0.05). Consequently, it was considered that the quantitative analysis that used a variety of function parameters index would be useful for evaluating the function of the salivary glands of the patients with dry mouth as an objective and standardized information.
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KEYWORD
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Salivary Glands Scan, Function Parameter Index, Time-Activity Curve, Dry Mouth
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